September 2009

adults in the United States with a mild form of asthma may not need to take daily steroid doses

banner1a adults in the United States with a mild form of asthma may not need to take daily steroid doses http://www.healasthma.com

231. (WA) – April 14, 2005 For mild asthma, less may be more An estimated 4 million adults in the United States with a mild form of asthma may not need to take daily steroid doses but can instead use the drug only as needed to control symptoms, according to a new study supported by the National Institutes of Health. The change would make drug use more convenient, minimize side effects from the powerful drugs and possibly save the nation as much as $2 billion per year. The study results do not apply to the 10 million adults with more severe ….. (TX) – January 27, 2005 HEALTH & MEDICINE Pregnancy needn’t halt asthma drug use Illness is more dangerous than the medication, study suggests Federal experts have issued guidelines advising women with asthma not to stop their medications during pregnancy. The guidelines, published in this month’s Journal of Allergy and Clinical Immunology, call asthma drugs less of a risk to mother and fetus than asthma attacks. The advice was issued by a panel of the National Asthma Education and Prevention Program. An estimated 3. 7 to 8. 4 percent of pregnant women have asthma, an inflammation and constriction of the airways ….. – December 8, 2002 Cops 08 Births Hospitals release the names of only those patients who sign consent forms. Great River Medical Center Dec. 3 Jim and Julie Belger, Burlington, girl Arrests/citations Reports are taken directly from the daily logs of area law enforcement agencies. Some agencies do not differentiate between arrests and citations. Burlington Saturday 3:28 a. m. Riverfront at south railroad bridge. Bradley Smyth, 29, 812 Emmett St. : open burning. 2:46 a. m. 222 Hayes Court ….. . – March 1, 2001 INTRUDER MAKES LIFE CHAOTIC It’s Kody Hollaway’s 12th birthday, and his mother is in the kitchen making his favorite dinner of meatballs with rice and parsley. She’s mixing the meat and arguing with Elizabeth, 11, standing at her elbow, about just how short she can cut her hair. The twins, who just turned 9, are sparring in the garage, each wearing one big red boxing glove and shouting “hi-yah!”Destany, 10, is singing Que Sera Sera, spinning on the …. – November 22, 2000 Police Say Man Forced Wife To Overdose PASSAIC — A man tried to kill his wife by forcing her to take a mixture of prescription drugs while he held a knife to her throat, police said. Sgt. Richard Williams, a police department spokesman, said Tuesday that detectives charged Richard Texidor, 44, of Lexington Avenue, in the attack on his wife, 41-year-old Leonila Texidor. She was taken to St. Mary’s Hospital in Passaic and was listed in fair condition Tuesday afternoon, a spokeswoman said. Williams said there was a ….. The Florida Times-Union – May 9, 2000 Checkup EATING RESPONSIBLY Trying to eat responsibly and willing to spend time at your computer in order to do it? The Department of Agriculture has a new Web site for you. At the Interactive Healthy Eating Index on www. usda. gov/cnpp, you fill out a form detailing all the food you’ve consumed over the past 24 hours. (Presumably this includes the things you ate standing in front of the refrigerator at night when no one was looking. ) The site will quickly calculate how your ….. – April 29, 2000 News capsules Minister is going to prison for assaulting teacher BOSTON (AP) — A minister accused of assaulting a teacher for giving his daughter a D-minus on her report card was sentenced to 2 1/2 years in prison Friday. A jury convicted Dale Robinson, 36, of assault and battery and disturbing the peace. Judge Rosalind Miller gave Robinson the maximum penalty for assault and battery and ordered him to serve 10 additional days on the disturbing-the-peace charge. Teacher Antonio Centeio lost …. 238. (FL) – December 11, 1999 Dr. Paul G. Donohue ASTHMA AND ATHLETICS ARE COMPATIBLE DEAR DR. DONOHUE: I am an overweight asthmatic. I am trying to lose weight so that I can look better. Exercise makes it difficult for me to breathe. I have had asthma since I was 3. I seek help in finding a way to participate in normal teen-ager activiti es. My doctor is no help at all. – N. Y. ANSWER: Most people with asthma can gain an upper hand on the illness so they can exercise and participate in sports. In the 1988 Olympics games, 52 of the …. (WV) – August 20, 1999 PEIA uses funds to add 21 drugs to ‘preferred’ list THE ASSOCIATED PRESS Officials of the state’s Public Employees Insurance Agency have decided to spend $1 million approved during a special legislative session this week on drugs. PEIA will add 21 drugs to its preferred prescription list beginning Sept. 1, director Bob Ayers said Thursday. New drug policies that went into effect July 1 require the agency’s 150, 000 subscribers to pay more for drugs that are not on the list and have no generic ….. The Dallas Morning News – July 11, 1999 HEALTHY ATTITUDE Cigna keeps a low profile to maintain good working relationships, big profits At a wrestling match that pits doctors and consumers against HMOs, Cigna HealthCare of Texas occupies a comfortable ringside seat. While other local health maintenance organizations are losing money and struggling to satisfy members, Cigna has escaped this punishment. It ranks highest in member satisfaction and lowest in doctor turnover. At the same time, it charges the highest premiums and consistently earns the largest profit of any local insurer. And Cigna has managed to elude ….

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FDA looks into Singulair, reports of suicidal thoughts The Food and Drug Administration is investigating anecdotal reports that people who use Singulair, are at greater risk for suicide.

banner1a FDA looks into Singulair, reports of suicidal thoughts The Food and Drug Administration is investigating anecdotal reports that people who use Singulair, are at greater risk for suicide. http://www.healasthma.com

221. Sauk Valley Newspapers (Dixon-Sterling, IL) – March 29, 2008 FDA looks into Singulair, reports of suicidal thoughts Gannett News Service The Food and Drug Administration is investigating anecdotal reports that people who use Singulair, the popular asthma and allergy drug, are at greater risk for suicidal thoughts and suicide. Singulair is a pill prescribed to treat asthma and hay fever symptoms such as sneezing and a nose that is stuffy, runny or itchy. It blocks an inflammation pathway in the body that can cause both asthma and allergy symptoms. It was approved for treating asthma in 1998, and …. (MO) – March 28, 2008 FDA investigates drug suicide link WASHINGTON (AP) – The Food and Drug Administration said yesterday it is investigating a possible link between Merck’s best-selling Singulair and suicide. FDA said it is reviewing a handful of reports involving mood changes, suicidal behavior and suicide in patients who have taken the popular allergy and asthma drug. With sales of $4. 3 billion last year, Singulair is used by millions of patients in the United States, according to Merck. First approved in 1998, ….. High Point Enterprise (NC) – March 28, 2008 FDA probes possible allergy drug, suicide link WASHINGTON (AP) – The Food and Drug Administration said Thursday it is investigating a possible link between Merck’s best-selling Singulair and suicide. FDA said it is reviewing a handful of reports involving mood changes, suicidal behavior and suicide in patients who have taken the popular allergy and asthma drug. With sales of $4. 3 billion last year, Singulair isused by millions of patients in the U. S, according to Merck. First approved in 1998, it’s part of ….. – March 28, 2008 Doctors surprised by probe linking Singulair to suicide The federal Food and Drug Administration is studying a possible link between Singulair, Merck & Co. ’s hugely popular asthma drug, and suicide. The agency will review reports it received about behavior and mood changes, suicidal thoughts and suicide itself among patients on the drug. The FDA did not say how many reports it had received. Merck noted it was a “very limited number” involving both adults and children. Merck’s ….. (TX) – March 28, 2008 Lt. Gen. Martin Dempsey set to assume command of wars in Iraq and Afghanistan WASHINGTON (AP) – One of the Army’s most Iraq- generals is taking charge, at least temporarily, of arguably the most important command in the U. S. military, with responsibility for the wars in Iraq and Afghanistan. In a ceremony Friday at MacDill Air Force Base, Fla. , Lt. Gen. Martin Dempsey is to assume command of U. S. Central Command from Navy Adm. William J. Fallon, who announced unexpectedly on March 11 that he was quitting. Fallon cited press reports that he was at …. High Point Enterprise (NC) – March 28, 2008 FDA probes possible allergy drug, suicide link WASHINGTON (AP) – The Food and Drug Administration said Thursday it is investigating a possible link between Merck’s best-selling Singulair and suicide. FDA said it is reviewing a handful of reports involving mood changes, suicidal behavior and suicide in patients who have taken the popular allergy and asthma drug. With sales of $4. 3 billion last year, Singulair isused by millions of patients in the U. S, according to Merck. First approved in 1998, it’s part of ….. PharmaGazette – March 27, 2008 Suicidal on Singulair? Mar. 27, 2008 ( PharmaGazette delivered by Newstex) — The newest drug that has been linked to suicidal behavior, in both adults and children, is the ever popular asthma medication Singulair. This drug, used to treat allergy type symptoms such as stuffy nose, sneezing as well as asthma, is now under scrutiny after reports were made concerning mood and behavior changes and suicidal thoughts in patients taking the drug. The U. S Food and Drug Administration claims that there is no ….. Observer, The (London, England) – June 10, 2007 The Observer: ALLERGIES: Hay fever Hay fever is the most common allergy in Western countries, affecting around 15 per cent of the population. In the UK, the rates have soared and it is staggering to think that some 26 per cent of the population now suffer from it, usually for around two to three months each year. The condition, also known as seasonal allergic rhinitis, is often thought of as a minor ailment, whereas in reality the constant tiredness and sneezing that is part of the condition can have a very real impact on ….. – April 3, 2006 Prednisone just one of many asthma drugs DEAR DR. DONOHUE: My wife has had asthma since 1998. She weighed 130 pounds then. She has been on prednisone for a few years, and her weight has gone up to 174 and it is all in her middle. Is there anything besides prednisone that would work for her? — M. D. Asthma makes people’s airways (bronchi) very sensitive to the slightest irritation. If they breathe things that wouldn’t bother the rest of us, their airways constrict, and that makes the passage of air into and ….. – April 3, 2006 Prednisone just one of many asthma drugs DEAR DR. DONOHUE: My wife has had asthma since 1998. She weighed 130 pounds then. She has been on prednisone for a few years, and her weight has gone up to 174 and it is all in her middle. Is there anything besides prednisone that would work for her? — M. D. Asthma makes people’s airways (bronchi) very sensitive to the slightest irritation. If they breathe things that wouldn’t bother the rest of us, their airways constrict, and that makes the passage of air into and ….

try1 FDA looks into Singulair, reports of suicidal thoughts The Food and Drug Administration is investigating anecdotal reports that people who use Singulair, are at greater risk for suicide. http://www.healasthma.com

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Cortisone inhalers have revolutionized asthma treatment

banner1a Cortisone inhalers have revolutionized asthma treatment http://www.healasthma.com

251. – April 3, 1994 Drugs Help Asthmatics Breathe ANAHEIM, Calif. A new class of drugs appears to help patients with mild to moderate asthma breathe easier, according to two preliminary studies presented at an allergy meeting here. The drugs, called leukotriene-receptor antagonists, act to reduce the inflammation in the airways that is thought to be responsible for causing asthma, said Dr. William Howland III, medical director of HealthQuest Therapy and Research Institute in Austin, Texas. Asthma is thought to be caused by a type of ….. AFX-CNF (UK) – April 24, 2008 AFX CNF: AstraZeneca PLC – 1st Quarter Results (2 of 2) RNS Number:0203T AstraZeneca PLC 24 April 2008 Consolidated Income Statement 2008 2007 For the quarter ended 31 March $m $m Sales 7, 677 6, 966 Cost of sales (1, 502) (1, 486) Distribution costs (66) (61) Research and development (1, 236) (1, 170) Selling, general and administrative costs (2, 737) (2, 217) Other operating income and expense 121 138 Operating profit 2, 257 2, 170 Finance income 258 247 Finance expense (372) (150) Profit before tax 2, 143 2, 267 Taxation (638) (703) Profit for the period ….. – June 8, 2003 Going straight to the consumer. , Drug companies use more TV advertising. companies use more television advertisingBy Sandy Miller Times-News writerTWIN FALLS — If you want to know one of the biggest reasons for rising prescription costs, you need look no farther than your television screen. During breaks of your favorite TV shows, you’ll see 40-something-year-old arthritic ice skater Dorothy Hamill still able to do early morning glides around the rink thanks to a new drug called Vioxx. And what used to just be plain old heartburn is now “acid ….. Sun-Sentinel – March 22, 1999 ASTHMA SPRAY SAFETY Dear Dr. Donohue: In light of recent warnings about cortisone inhalers and children’s growth, I took my 14-year-old son off his. When he tried alternative treatments, he was a mess. He started back on the spray and his symptoms disappeared in days. Is his body addicted to the spray? — S. A. Dear S. A. : Cortisone inhalers have revolutionized asthma treatment. On the downside, they might stunt growth. Uncontrolled asthma might stunt growth, too. Whether cortisone inhalers will ….. El Nuevo Herald – January 3, 1999 UNA ESTACIÓN IDEAL PARA EL ASMA Se habla de las vacaciones navideñas; pero para ciertas enfermedades, como el asma, ésta no es la mejor época. Los días son frescos y muchos detalles que acompañan a estas fiestas son para los que padecen esta enfermedad, una amenaza. Esta amenaza es especialmente fuerte para los jóvenes asmáticos, quienes se sueltan las riendas para disfrutar, y se olvidan de su asma, cambiando sus rutinas diarias. Como muchos medicamentos se administran mediante inhaladores, cuyo empleo en esta ….. (CT) – December 4, 1998 Asthma drug has serious complications Doctors should carefully watch asthma patients who take the drug Singulair for signs of a rare but serious complication called Curg-Strauss syndrome, manufacturer Merck & Co. warned Thursday. Curg-Strauss syndrome is a tissue disorder that sometimes strikes adult asthma patients and, if untreated, can destroy organs. Merck said Thursday that it has received fewer than 20 reports of Singulair patients developing symptoms of Curg-Strauss, out of 600, 000 people worldwide who have ….. (Riverside, CA) – December 4, 1998 Doctors warned about asthma drug Doctors should carefully watch asthma patients who take the drug Singulair for signs of a rare but serious complication called Churg-Strauss syndrome, manufacturer Merck & Co. warned Thursday. Churg-Strauss syndrome is a tissue disorder that sometimes strikes adult asthma patients and, if untreated, can destroy organs. Merck said Thursday that it has received fewer than 20 reports of Singulair patients developing symptoms of Churg-Strauss, out of 600, 000 people worldwide who ….. Financial Times (London, England) – October 28, 1998 COMPANIES & FINANCE: UK: Zeneca to take Pounds 130m sterling hit Chemicals, Speciality. Pharmaceuticals, Pharmaceuticals. Zeneca’s shares lost some of their recent shine yesterday after the pharmaceuticals and agrochemicals group estimated that sterling’s strength would knock Pounds 130m from full-year profits. In August, Zeneca expected a full-year currency effect of Pounds 110m, based on prevailing exchange rates. Zeneca’s shares, which had risen 25 per cent to Pounds 23. 37 in the two weeks leading up to the ….. Los Angeles Times – February 24, 1998 Merck Soars on FDA’s OK of Asthma Drug Merck & Co. said it won U. S. Food and Drug Administration approval of its potential blockbuster asthma drug Singulair, sending the company’s shares up nearly 5%. Merck shares rose $5. 94 to close at $130. 63 in active trading on the New York Stock Exchange on Monday. Peak worldwide sales of Singulair could exceed $1 billion a year, putting pressure on competitors Zeneca and Abbott Laboratories, and asthma-inhaler makers such as Glaxo Wellcome, Schering-Plough Corp ….. . Newsday (Melville, NY) – October 30, 1997 Industry Takes Ad Medicine / Wherever one looks, the drug makers are busy. YOU SEE the ads all over. Commuter trains into Manhattan carry posters touting the prescription drug Claritin “for seasonal allergy relief” and others for Zyban (”It’s here”) that offers a toll-free number for what callers will learn is a pill to help smokers quit. On prime-time TV, the maker of another allergy fighter has been hammering its Allegra name into viewers’ heads by showing a woman wind-surfing through a ….

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octors should carefully watch asthma patients who take the drug Singulair

banner1a octors should carefully watch asthma patients who take the drug Singulair  http://www.healasthma.com

241. THE – December 14, 1998 SEASON OF SHARING When It’s Hard to Stay Afloat Foster City couple labors with life She starts with the big turquoise ones. Every morning, and again every evening, Pam Alvarado works her way through the handful of pills, from biggest to smallest. Next up are the pale green-and-white capsules, then the pink tablets and the white lozenges. They go down easier in this order. When you take 20 pills a day, you have to have a system. Alvarado, 52, is feeling poorly. In fact, everyone in this household in a Foster City seniors’ residence is ….. (FL) – October 25, 1998 THREE ILLNESSES CAN CRIPPLE LUNGS Dear Dr. Donohue: I have had bronchitis for seven months. Will you explain the difference between bronchitis, emphysema and asthma? I’m so sick of using inhalers. Is there anything else? I blame my troubles on El Nino. What do you think? – E. M. Dear E. M. : Chronic bronchitis is a cough that lingers for at least three months in two consecutive years. Along with the cough, chronic bronchitis produces copious amounts of thick, sticky mucus. “Chronic” is ….. – October 25, 1998 EMPHYSEMA, ASTHMA AFFECT BREATHING Dear Dr. Donohue: I have had bronchitis for seven months. Will you explain the difference between bronchitis, emphysema and asthma? I’m so sick of using inhalers. Is there anything else? I blame my troubles on El Nino. What do you think? Chronic bronchitis is a cough that lingers for at least three months in two consecutive years. Along with the cough, chronic bronchitis produces copious amounts of thick, sticky mucus. “Chronic” is used to distinguish ….. Rocky Mountain News (CO) – April 26, 1998 ALLERGIES TAKE A BREATHER DESIGNER ANTIBODIES MAY BRING THE SPRING SNEEZE TO ITS KNEES As anyone with a nose knows, this spring’s pollen crop has arrived early and often across much of the country, courtesy of the mild, wet El Nino winter. Spores from trees, followed by grasses, followed by weeds, with a bonus dollop of molds, are expected to be seizing the sinuses and clogging up the bronchial tubes from now until the fall frosts. An estimated 35 million Americans suffer from allergic rhinitis or hay fever and about 15 million have asthma, with much overlap …. 245. Times, The (London, England) – April 7, 1993 Drug shares stay under the weather, Stock Market GOOD news is a rare commodity these days in the pharmaceutical sector, which has suffered more than its fair share of setbacks in the past six months. Regarded as a safe haven for investors during times of economic hardship, pharmaceutical companies are emerging from the recession looking positively shell-shocked. These days they appear friendless on both sides of the Atlantic and their prospects remain gloomy. The pharmaceutical industry was dealt a blow with the election of President …. 246. (FL) – May 5, 2007 How Should Pregnant Women Deal With Asthma? , By DENNIS LEDFORD, M. D. Tribune correspondent Asthma is one of the most common chronic conditions affecting pregnancy. Approximately 4 percent to 8 percent of pregnant women suffer from asthma. Women whose asthma is well controlled throughout pregnancy have an excellent chance for a normal pregnancy and a healthy baby. However, severe or poorly treated asthma is associated with premature birth, increased need for Caesarean sections, elevated blood pressure for the mother and growth retardation for the ….. Times Union, The (Albany, NY) – December 4, 1998 DRUG MANUFACTURER ISSUES WARNING ABOUT MEDICATION WASHINGTON — Doctors should carefully watch asthma patients who take the drug Singulair for signs of a rare but serious complication called Churg-Strauss syndrome, manufacturer Merck & Co. warned Thursday. Churg-Strauss syndrome is a tissue disorder that sometimes strikes adult asthma patients and, if untreated, can destroy organs. Merck said Thursday that it has received fewer than 20 reports of Singulair patients developing symptoms of Churg-Strauss, out of 600, 000 ….. Birmingham Post, The (England) – August 7, 1998 The Birmingham Post: Business: Shares slide as Zeneca disappoints at half time Shares in Zeneca dropped sharply yesterday after the drugs giant revealed a big fall in half-time profits. The company, a persistent subject of takeover rumours in the City, said the strong pound had taken GBP81 million off the bottom line, and was likely to cost it about GBP110 million in full-year profits. Pre-tax profits for the first six months of the year came in at GBP626 million, lower than analysts had been forecasting and down from GBP669 million a year ago. The lower figure ….. Observer, The (London, England) – May 17, 1998 The Observer: Money: Zeneca coming on a treat: Stockwatch: Investment KEEP an eye on Zeneca. The shares, at 2511p, were given a fillip on Friday when data in the Lancet showed that Nolvadex, its anti-cancer treatment, cuts the risk of recurrence of breast cancer after surgery. Nolvadex comes off patent in the US in 2002, but it may be cleared for preventative treatment, which could cushion future sales by up to pounds 150 million a year. Zeneca’s current best-seller is heart-failure treatment Zestril, with pounds 632m of sales last year. It ….. Times, The (London, England) – March 12, 1997 Cupboard far from bare, Tempus THE giddy rise of Zeneca’s share price is enough to give investors altitude sickness. Less than two years ago, the price soared through the Pounds 10 barrier in a fever of takeover speculation, and sceptics warned the market that it could never last. Yesterday, shares in the drugs company leapt to Pounds 19. 38, before falling back to end a hectic day 42p lower at Pounds 18. 60 1/2. Zeneca is now valued at about Pounds 18 billion. Sir David Barnes, Zeneca’s chief ….

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Asthma is being underdiagnosed and undertreated

banner1a Asthma is being underdiagnosed and undertreated http://www.healasthma.com

261. Delaware County Daily Times (Primos – Upper Darby, PA) – July 25, 1997 Briefly (wire) WASHINGTON (AP) — A human protein thought to be a useless byproduct of insulin — and that drug companies now throw away — may protect against devastating heart and nerve damage that diabetes causes. A new study in rats backs up a handful of reports from Sweden suggesting human diabetics may benefit from the substance. And scientists say the findings, to be published Friday in the journal Science, are intriguing enough for in-depth study of whether adding C-peptide to insulin therapy really …. 262. (OH) – July 24, 1997 BRIEF Jewell sues ` ‘ over coverage of bombing NEW YORK – Richard Jewell sued the for $15 million Wednesday, saying he was libeled and defamed by the newspaper’s “fictionalized” coverage of him while he was a suspect in the Olympic Park bombing. The federal lawsuit cites a series of articles, headlines, photographs and editorial cartoons that appeared in the newspaper in the days after The Atlanta Journal and The Atlanta ….. (Walnut Creek, CA) – April 15, 1997 GROUP URGES AGGRESSIVE ASTHMA TREATMENT “Asthma is being underdiagnosed and undertreated, ” said Dr. Shirley Murphy, chair of the National Asthma Education & Prevention Program. “It’s time professionals take this disease seriously and treat it aggressively. “With that goal in mind, the NAEPP has issued new, updated clinical guidelines for treating asthma. The original guidelines were published in 1991. The new guidelines reaffirm that asthma is a chronic …. Sun-Sentinel – October 31, 1996 PAIN PATCH CAN KILL Dear People’s Pharmacy: Please warn about the dangers of Duragesic patches. This transdermal system contains fentanyl, a potent opioid, and is responsible for accidental deaths. Even after 72 hours of use, a Duragesic patch still has a lethal dose of fentanyl left in it if it is orally ingested. I learned this the hard way. My 14-year-old son died in less than an hour after chewing on a used patch. I lost the lawsuit I brought because the jury decided that “Keep out ….. – March 29, 1996 DAILY DIGEST Belk may be a suitor for Leggett Stores Leggett Stores Inc. may be considering a buyout offer from yet another major retailer. Retail industry analysts have added Belk to the list of possible suitors, which, they speculate, already includes Proffitt’s and Dillard. Knoxville, Tenn. -based Proffitt’s has four Hampton Roads locations; Dillard, of Little Rock, Ark. , has no Hampton Roads locations yet, but plans to open one in the MacArthur Center, a proposed downtown ….. Family Life – March 1, 2000 Health FLOSSING FUN Gum disease doesn’t affect only adults. A recent study found that 39 percent of children in the United States have some form of periodontal disease. “Once a child can tie his shoes, he should be flossing on a daily basis, too, ” says Ned Savide, D. D. S. , attending pediatric dentist at Hope Children’s Hospital in Oak Lawn, IL. “Flossing is the best way to get between teeth; brushing cleans only the tooth ….. – December 6, 1998 Doctors warned about asthma drug WASHINGTON (AP) — Asthma patients who take the drug Singulair should be watched carefully by their doctors for signs of a rare but serious complication called Churg-Strauss syndrome, drug-maker Merck & Co. advises. Churg-Strauss syndrome is a tissue disorder that sometimes strikes adult asthma patients and, if untreated, can destroy organs. Merck said Thursday it has received fewer than 20 reports of Singulair patients developing symptoms of Churg-Strauss, out of 600, 000 ….. – December 3, 1998 Doctors warned about asthma drug Doctors should carefully watch asthma patients who take the drug Singulair for signs of a rare but serious complication called Churg-Strauss syndrome, manufacturer Merck & Co. warned Thursday. Churg-Strauss syndrome is a tissue disorder that sometimes strikes adult asthma patients and, if untreated, can destroy organs. Merck said Thursday that it has received fewer than 20 reports of Singulair patients developing symptoms of Churg-Strauss, out of 600, 000 people worldwide ….. Newsday (Melville, NY) – May 9, 2000 Promising Allergy Therapies / Advanced drugs appear more effective than antihistamines SEVERAL NEW TREATMENT options currently under investigation seem to hold out the promise of easing the seasonal battle against allergies. Allergies occur when an antibody in the immune system called immunoglobulin E, or IgE, attaches to cells in the body called mast cells. When the cells come into contact with an allergen – i. e. , pollen, cat, dog or dust-it triggers the release of chemicals such as histamines and leukotrienes, which cause runny noses, nasal congestion, itchiness, watery …. 270. – December 4, 1998 Doctors warned about asthma drug Asthma patients who take the drug Singulair should be watched carefully by their doctors for signs of a rare but serious complication called Churg-Strauss syndrome, drug-maker Merck & Co. advises. Churg-Strauss syndrome is a tissue disorder that sometimes strikes adult asthma patients and, if untreated, can destroy organs. Merck said Thursday it has received fewer than 20 reports of Singulair patients developing symptoms of Churg-Strauss, out of 600, 000 people worldwide ….

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FDA Investigates Merck’s Singulair for Suicide Risk. Merck’s Singulair may be linked to suicide as well as changes in mood and behavior

banner1a FDA Investigates Mercks Singulair for Suicide Risk. Mercks Singulair may be linked to suicide as well as changes in mood and behavior http://www.healasthma.com

291. Herald and the Sunday Herald, The (Glasgow, Scotland) – August 7, 1998 The Herald (United Kingdom): Business: No smoke without fire Zeneca bid chatter unlikely to die down ZENECA’S pharmaceutical activities are what interest most people about the group, but it must be remembered that it is also the world’s third-largest agrochemical producer and this business generates 30% ofprofits. Genetically-modified crops are beginning to make an impact on agrochemicals. For all the opposition on this side of the Atlantic, genetically-modified seed is making big inroads on the US farming scene, notably in soya, maize and cotton. The …. The Kansas City Star – December 5, 1998 The morning memo BankAmerica brokerage jobs BankAmerica Corp. said Friday that it will eliminate 300 jobs from its brokerage unit that sells investments to retail customers as the nation’s largest bank consolidates units after its merger with NationsBank Corp. Charlotte, N. C. -based BankAmerica will eliminate the broker and support staff jobs across the country from both NationsBanc Investments Inc. and BA Investment Services, said spokeswoman Ann Anderson. Anderson said she didn’t …. 3. USA TODAY – May 30, 2000 A very real interest in new drugs Researchers’ financial ties to industry are big concern in academia ”Is Academic Medicine For Sale? ” Marcia Angell, editor in chief of The New England Journal of Medicine, asked that pointed question in an editorial that appeared the same week her successor was named. Though the editorial in the May 18 edition did not discuss Jeffrey Drazen and his financial ties to the pharmaceutical industry, it was an uncomfortable reminder that the new editor in chief of The New England Journal of Medicine represents …. 4. South Florida Sun-Sentinel (Fort Lauderdale, FL) – August 12, 2005 DR. PAUL DONOHUE GOOD HEALTH Dear Dr. Donohue: I have had hives for almost three years. They pop up anywhere on my body. Sometimes my hands swell, too. I have seen a dermatologist, an allergist and a rheumatologist. Nothing has worked so far. Do you have any ideas? — D. F. Dear D. F. : Allergies, medicines such as ACE inhibitors and anti-inflammatory drugs, thyroid-gland disorders, parasite infections and lupus are some of the hidden causes of recurrent crops of hives. And the hand-swelling, called angioedema, is a …. 5. – April 1, 1997 INHALING STEROIDS FOR ASTHMA PRODUCES FEWER SIDE EFFECTS DEAR DR. GOTT: For 10 years, I have had asthma that I can control only by taking prednisone pills. Because of the side effects of the drug, I would like to discontinue it but have been unable to do so. Are there any vitamins or herbs that I might substitute? Unfortunately, no. Prednisone and similar steroid medicines basically shut off the immune system. Hence, they are useful in treating hyperimmune disorders (such as lupus and acute allergies) and asthma, a breathing abnormality …. 6. Newstex Blogs (USA) – June 13, 2009 Twitter activity by Aircrew Health Jun. 12, 2009 ( Newstex Newstwits delivered by Newstex) Latest from @whonews Influenza A(H1N1) – update 48 http://tinyurl. com/luv466 #H1N1 #swineflu #influenza #pandemic #WHO 06-12-2009 at 20:38:09 UTC Thank you @HMCRespiratory @diseaseaday @PandiBearSRT #followfriday 06-12-2009 at 20:42:31 UTC Communication expert endorses WHO’s declaration delay http://bit. ly/biVWW (via @CIDRAP) #H1N1 #influenza #pandemic #communication #policy 06-12-2009 at …. 7. MondayMorning (USA) – March 31, 2008 FDA Investigates Merck’s Singulair for Suicide Risk. Merck & Co. ’s (Whitehouse Station NJ) Singulair may be linked to suicide as well as changes in mood and behavior, the Food and Drug Administration said in announcing a review of the company’s top-selling asthma drug. FDA said it is working with Merck to evaluate studies and patient reports, the agency said in a notice on its Web site. The examination may take as long as nine months. The company declined to say how many deaths were reported. Singulair is …. 8. Winchester (VA) – January 24, 2005 Pregnant Women Should Still Treat Asthma Federal experts have issued new guidelines advising women with asthma not to stop their medications during pregnancy. The guidelines, published in this month’s Journal of Allergy and Clinical Immunology, call asthma drugs less of a risk to mother and fetus than asthma attacks. The advice is issued by a panel of the National Asthma Education and Prevention Program. An estimated 3. 7 to 8. 4 percent of pregnant women have asthma, an inflammation and constriction of the airways that …. 9. (WV) – June 20, 2000 The sneezing season Doctors offer tests, remedies to treat sniffles, red eyes MOST people take for granted romping with their pets, mowing grass and sleeping soundly on a soft feather pillow. Not William Lingan. And not 5-year-old James David Lingan. The Big Chimney father and son suffer from allergies and asthma. James was diagnosed nearly three years ago, after several scary trips with his parents to the emergency room at Women and Children’s Hospital. For his dad, the definitive diagnosis came just last week from Dr. Nasim Sheikh, a local …. 300. Stuart News, The (FL) – April 1, 1997 ASTHMATICS HAVE TREATMENT OPTIONS DEAR DR. GOTT: For 10 years, I have had asthma that I can control only by taking prednisone pills. Because of the side effects of the drug, I would like to discontinue it but have been unable to do so. Are there any vitamins or herbs that I might substitute? DEAR READER: Unfortunately, no. Prednisone and similar steroid medicines basically shut off the immune system. Hence, they are useful in treating hyper-immune disorders (such as lupus and acute allergies) and asthma, a breathing ….

try1 FDA Investigates Mercks Singulair for Suicide Risk. Mercks Singulair may be linked to suicide as well as changes in mood and behavior http://www.healasthma.com

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Cold Weather Can Bring On Asthma Many people are diagnosed with asthma, the first symptoms of which are chest tightness or shortness of breath

banner1a Cold Weather Can Bring On Asthma Many people are diagnosed with asthma, the first symptoms of which are chest tightness or shortness of breath http://www.healasthma.com

301. Time – October 14, 1996 NOTEBOOK WINNERS & LOSERS AMERICA IN FLIGHT [WINNERS] VALUJET Troubled carrier returns to the skies with seven planes and $19 one-way fares PAN AM Once proud international line is reincarnated with domestic flights–for now DELTA New low-cost Delta Express division begins service to capture slice of rich leisure market [& LOSERS] KIWI INTERNATIONAL Filing for bankruptcy, company cuts service by two-thirds and faces renewed competition AMERICA WEST …. Nevada Appeal (Carson City, NV) – January 24, 2005 Pregnant? Treat your asthma seriously Breathe Easier Federal experts have issued new guidelines advising women with asthma not to stop their medications during pregnancy. The guidelines, published in this month’s Journal of Allergy and Clinical Immunology, call asthma drugs less of a risk to mother and fetus than asthma attacks. The advice is issued by a panel of the National Asthma Education and Prevention Program. Taking It Seriously An estimated 3. 7 to 8. 4 percent of pregnant women have asthma, an ….. (DC) – January 18, 2005 Pregnant? Treat Your Asthma Breathe Easier Federal experts have issued new guidelines advising women with asthma not to stop their medications during pregnancy. The guidelines, published in this month’s Journal of Allergy and Clinical Immunology, call asthma drugs less of a risk to mother and fetus than asthma attacks. The advice is issued by a panel of the National Asthma Education and Prevention Program. Taking It Seriously An estimated 3. 7 to 8. 4 percent of pregnant women have asthma, an ….. Hunterdon County Democrat (Flemington, NJ) – December 19, 2002 Dr. Edwin Schulhafer HEALTH CAPSULE Winter’s Cold Weather Can Bring On Asthma Many people are diagnosed with asthma, the first symptoms of which are chest tightness or shortness of breath, as the weather grows cold. Outdoor running in the cold air is more likely to result in exercise-induced asthma than running in summer conditions. Also, as indoor heating increases, dry indoor air is filled with dormant dust mite and animal dander particles that conspire against those with allergies and ….. Parramatta Advertiser (Sydney, Australia) – October 17, 2001 Asthma plan boon for kids’ wellbeing While there are many effective treatments for asthma, one of the most important factors in achieving asthma control is to make sure your child has an Asthma Action Plan developed in consultation with the family doctor. Parents who have been educated about the causes and treatment of asthma cope better and their children’s asthma is better controlled too. Prof Kim Oates, Chief Executive, the Children’s Hospital at Westmead. MORE than two million Australians have …. – May 8, 2000 MINI HINTS/HELP FOR CHILDREN * Children do not grieve. * Children get over loss quickly. * Children should be shielded from loss. These are some of the myths about how children and adolescents deal with grief – myths that the Hospice Foundation of America is dedicated this year to abolishing. Children do grieve when someone they love dies, and they need help from their families, teachers and other adults to learn how to live with the loss. The foundation has published a book, “Children, ….. – December 11, 1999 Asthma, athletics compatible Q: I am an overweight asthmatic. I am trying to lose weight so that I can look better. Exercise makes it difficult for me to breathe. I have had asthma since I was 3. I seek help in finding a way to participate in normal teen-ager activities. My doctor is no help at all. — N. Y. A: Most people with asthma can gain an upper hand on the illness so they can exercise and participate in sports. Today, doctors realize asthma is a chronic inflammation of the airways, and they keep patients on ….. (Walnut Creek, CA) – December 7, 1999 ASTHMA NEED NOT PROHIBIT EXERCISE Q: I am an overweight asthmatic. I am trying to lose weight so that I can look better. Exercise makes it difficult for me to breathe. I have had asthma since I was 3. I seek help in finding a way to participate in normal teen-age activities. My doctor is no help at all. A: Most people with asthma can gain an upper hand on the illness so they can exercise and participate in sports. In the 1988 Olympics games, 52 of the 667 athletes suffered from asthma. They had the illness under such good ….. (Walnut Creek, CA) – December 7, 1999 ASTHMA NEED NOT PROHIBIT EXERCISE Q: I am an overweight asthmatic. I am trying to lose weight so that I can look better. Exercise makes it difficult for me to breathe. I have had asthma since I was 3. I seek help in finding a way to participate in normal teen-age activities. My doctor is no help at all. A: Most people with asthma can gain an upper hand on the illness so they can exercise and participate in sports. In the 1988 Olympics games, 52 of the 667 athletes suffered from asthma. They had the illness under such good ….. KNIGHT RIDDER/TRIBUNE BUSINESS NEWS – February 18, 1999 DAILY MAIL, LONDON, ANDREW ALEXANDER COLUMN Feb. 18–ZENECA HOPES ITS HONEYMOON WILL NOT END WITH A HEADACHE: My, how the child has grown! And now it is all set for a sparkling marriage. When Zeneca was spun out of ICI in 1993, it looked a healthy infant with its portfolio of drugs plus its less important agrochemicals and specialities businesses. Few would have thought Zeneca would now have a market value of UKpound 25 billion while ICI languishes at only UKpound 3. 9 billion. Later this year, when Zeneca merges with Swedish ….

try1 Cold Weather Can Bring On Asthma Many people are diagnosed with asthma, the first symptoms of which are chest tightness or shortness of breath http://www.healasthma.com

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zafirlukast (sold as Accolate) daily for 13 weeks had 90 percent more days without asthma symptoms

banner1a zafirlukast (sold as Accolate) daily for 13 weeks had 90 percent more days without asthma symptoms  http://www.healasthma.com

161. – February 23, 1998 Big Movers in the Stock Market Some of the stocks that moved substantially or traded heavily Monday on the New York Stock Exchange, Nasdaq Stock Market, and American Stock Exchange. NYSE Merck, up 5 15/16 at 130 5/8 The Food and Drug Administration cleared the drugmaker to begin selling its Singulair asthma drug next month. Singulair is one of a new class of oral asthma drugs that targets the causes of the disease, rather than symptoms. The first such drug to win FDA approval was Zeneca ….. Bismarck Tribune, The (ND) – April 1, 2008 Link between suicide, Singulair investigated WASHINGTON (AP) – The Food and Drug Administration said Thursday it is investigating a possible link between Merck’s best-selling Singulair and suicide. FDA said it is reviewing a handful of reports involving mood changes, suicidal behavior and suicide in patients who have taken the popular allergy and asthma drug. With sales of $4. 3 billion last year, Singulair is used by millions of patients in the U. S, according to Merck. First approved in 1998, it’s part of a ….. Winchester (VA) – March 28, 2008 FDA probes Singulair, suicide WASHINGTON – The Food and Drug Administration is investigating a possible link between Merck’s best-selling Singulair drug and suicide. FDA said on Thursday that it is reviewing a handful of reports involving mood changes, suicidal behavior and suicide in patients who have taken the popular allergy and asthma drug. With sales of $4. 3 billion last year, Singulair is used by millions of patients in the U. S, according to Merck. First approved in 1998, it is part of a class of ….. (NJ) – March 28, 2008 FDA probes possible link of Singulair with suicide The Food and Drug Administration said Thursday it is investigating a possible link between Merck’s best-selling Singulair and suicide. The FDA said it is reviewing a handful of reports involving mood changes, suicidal behavior and suicide in patients who have taken Merck’s popular allergy and asthma drug. With sales of $4. 3 billion last year, Singulair is used by millions of patients in the U. S, according to Merck. First approved in 1998, it’s part of ….. (CA) – February 10, 1997 NEW ASTHMA DRUGS CAN HELP PREVENT SYMPTOMS Regular use of one of the first of a new class of asthma drugs can help prevent symptoms in people with mild to moderate asthma, according to a new study. Of 146 asthmatics who used inhalers as needed, those who also took zafirlukast (sold as Accolate) daily for 13 weeks had 90 percent more days without asthma symptoms and 98 percent more days without episodes of asthma that disturbed their sleep or limited their activity than those who took placebo instead of zafirlukast. Zafirlukast ….. – June 15, 2009 FDA asks for warning on some asthma drugs The U. S. Food and Drug Administration has asked manufacturers to include a precaution in the labeling of some asthma drugs called leukotriene modifiers. The federal agency said the labeling should advise patients that some neuropsychiatric events have been reported by people taking montelukast (Singulair), zafirlukast (Accolate) and zileuton (Zyflo and Zyflo CR). Leukotrienes are chemicals the body releases in response to an inflammatory stimulus, such as when a person breathes in an ….. (MI) – March 28, 2008 In Brief FDA probing possible link between Singulair, suicide WASHINGTON – The Food and Drug Administration said Thursday it is investigating a possible link between Merck’s best-selling Singulair and suicide. The FDA said it is reviewing a handful of reports involving mood changes, suicidal behavior and suicide in patients who have taken the popular allergy and asthma drug. With sales of $4. 3 billion last year, Singulair is used by millions of patients in the U. S, ….. – June 23, 1997 ALLERGY POLICE // DOCTOR INVESTIGATES MEDICINES THAT COULD BRING SIGH OF RELIEF Dr. Anjuli Nayak likes to treat today’s patients with tomorrow’s medicine. Nayak is a local allergist. In her practice, she and her staff determine what patients are allergic to, then – if appropriate – give them injections of an allergen to gradually build up their immunity. That’s not unusual. There are several allergists in Bloomington-Normal. What is unusual is what goes on next door to her practice at 1300 Franklin Ave. , Suite 180, …. – March 28, 2008 FDA investigating link between allergy drug, suicide WASHINGTON — The Food and Drug Administration said Thursday it is investigating a possible link between Merck’s best-selling Singulair and suicide. The FDA said it is reviewing a handful of reports involving mood changes, suicidal behavior and suicide in patients who have taken the popular allergy and asthma drug. With sales of $4. 3 billion last year, Singulair is used by millions of patients in the U. S, according to Merck. First approved in 1998, ….. (WV) – March 28, 2008 FDA checking reported Singulair-suicide link WASHINGTON – The Food and Drug Administration said Thursday it is investigating a possible link between Merck’s best-selling Singulair and suicide. The FDA said it is reviewing a handful of reports involving mood changes, suicidal behavior and suicide in patients who have taken the popular allergy and asthma drug. With sales of $4. 3 billion last year, Singulair is used by millions of patients in the United States, according to Merck. First approved in 1998, it’s ….

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FDA probes suicide link to Singulair

banner1a FDA probes suicide link to Singulair http://www.healasthma.com

151. Evening Standard, The (London, England) – January 27, 1998 EVENING STANDARD: BUSINESS DAY: DRUGS SET UP ZENECA FOR AN EARNINGS HIGH DRUGS group Zeneca said today a better-than-expected performance from its pharmaceuticals side, particularly new products, should enable it to report earnings above its “aspirational growth rate” of 15% this year. Following a downturn on the agrochemicals side, however, the group said its trading performance for 1997 is expected to be “in line with market expectations”. Sales growth on the pharmaceuticals side accelerated in the fourth ….. Aberdeen Press & Journal (Scotland) – September 30, 2004 Aberdeen Press & Journal (UK): Farmlay top egg producer A North-east egg producer has won its second business accolade in a month. Strichen-based Farmlay Eggs, which earlier this month won Scotland’s best small busi- ness crown, has now been named the country’s top egg producer. The new accolate came during the Scottish Egg Quality Awards, which were decided at the Scottish Agricultural College’s Auchincruive cam-pus. Farmlay, run by husband and wife Robert and Ethel Chapman, faced competition from 20 ….. – February 23, 1998 Big Movers in the Stock Market Some of the stocks that are moving substantially or trading heavily today on the New York Stock Exchange, Nasdaq Stock Market, and American Stock Exchange. NYSE Merck, up 4 at 128 11/16 The Food and Drug Administration cleared the drugmaker to begin selling its Singulair asthma drug next month. Singulair is one of a new class of oral asthma drugs that targets the causes of the disease, rather than symptoms. The first such drug to win FDA approval was Zeneca ….. Bridgeton News (NJ) – March 28, 2008 FDA probes possible link between allergy drug, suicide WASHINGTON – The Food and Drug Administration said Thursday it is investigating a possible link between Merck’s best-selling Singulair and suicide. FDA said it is reviewing a handful of reports involving mood changes, suicidal behavior and suicide in patients who have taken the popular allergy and asthma drug. With sales of $4. 3 billion last year, Singulair is used by millions of patients in the U. S, according to Merck. First approved in 1998, it’s part of a ….. – March 28, 2008 FDA investigates possible Singulair, suicide link The Food and Drug Administration said Thursday it is investigating a possible link between Merck’s best-selling Singulair and suicide. FDA said it is reviewing a handful of reports involving mood changes, suicidal behavior and suicide in patients who have taken the popular allergy and asthma drug. With sales of $4. 3 billion last year, Singulair is used by millions of patients in the U. S, according to Merck. First approved in 1998, it’s part of a class of asthma ….. – March 28, 2008 FDA probes suicide link to Singulair The Food and Drug Administration said Thursday it is investigating a possible link between Merck’s best-selling Singulair and suicide. FDA said it is reviewing a handful of reports involving mood changes, suicidal behavior and suicide in patients who have taken the popular allergy and asthma drug. With sales of $4. 3 billion last year, Singulair is used by millions of patients in the U. S, according to Merck. First approved in 1998, it’s part of a class of asthma and ….. (FL) – May 5, 2007 How Should Pregnant Women Deal With Asthma? , By DENNIS LEDFORD, M. D. Tribune correspondent Asthma is one of the most common chronic conditions affecting pregnancy. Approximately 4 percent to 8 percent of pregnant women suffer from asthma. Women whose asthma is well controlled throughout pregnancy have an excellent chance for a normal pregnancy and a healthy baby. However, severe or poorly treated asthma is associated with premature birth, increased need for Caesarean sections, elevated blood pressure for the mother and growth retardation for the ….. wire Europe – February 23, 2006 SecurStar Wins International Security Award 2006 PRNewswire — Awarded in Best Disk Encryption, Best Email Security Solution, and Best Desktop Firewall Categories SecurStar GmbH with headquarter in Germany announced that the company’s products have gained SC Magazine Awards 2006. SecurStar’s encryption solutions have convinced readers as well as jury in all categories in which the company competed (best disk encryption, best email security solution, and best desktop firewall). With more than 1, 300 nominated products ….. MondayMorning (USA) – September 27, 1999 FDA ROUNDUP:. Careside Inc. (Culver City CA) was cleared to sell its test to detect carbon dioxide levels in blood. The test measures the total CO2 concentration in anti-coagulated blood, plasma, and serum, which aids in the diagnosis and treatment of patients with respiratory, kidney and metabolic disorders. * * Nidek Inc. (Fremont CA) received clearance to market its EAS-1000 Anterior Eye Segment Analysis System. The EAS-1000 is designed to provide clear, distinct anterior segment imaging of all pertinent ….. – February 23, 1998 Big Movers in the Stock Market Some of the stocks that are moving substantially or trading heavily today on the New York Stock Exchange, Nasdaq Stock Market, and American Stock Exchange. NYSE Merck, up 5 15/16 at 130 5/8 The Food and Drug Administration cleared the drugmaker to begin selling its Singulair asthma drug next month. Singulair is one of a new class of oral asthma drugs that targets the causes of the disease, rather than symptoms. The first such drug to win FDA approval was Zeneca ….

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people who use Singulair, the popular asthma and allergy drug, are at greater risk for suicidal thoughts and suicide

banner1a people who use Singulair, the popular asthma and allergy drug, are at greater risk for suicidal thoughts and suicide http://www.healasthma.com

321. AFX-CNF (UK) – April 24, 2008 AFX CNF: AstraZeneca PLC – 1st Quarter Results (1 of 2) RNS Number:0196T AstraZeneca PLC 24 April 2008 AstraZeneca PLC First Quarter Results 2008 – Core EPS increased by 9 percent at CER to $1. 28. – First quarter sales increased by 4 percent at CER to $7, 677 million. – Inclusion of MedImmune sales more than offset the decline in Toprol-XL((TM)) sales in the US. – Strong growth in Emerging Markets, with sales up 11 percent at CER. – Underlying business performance on track. Core EPS target increased to reflect year to date currency impact. – Revised ….. (NC) – April 24, 2008 Asthma poses serious health problem for children H HENDERSONVILLE— Asthma is the leading serious chronic illness of children in the U. S. , and it is the third leading cause of hospitalization among children younger than 15, according to the American Lung Association. This week, Dr. Chona S. Reguyal with Western Carolina Medical Associates in Fletcher answers some frequently asked questions about asthma. Question: What are the warning signs of asthma in children? Answer: Difficulty breathing, fast or rapid breathing, …. – April 3, 2008 IN BRIEF Sports Study suggests high mound a factor in pitchers’ injuries As baseball season begins, pitchers will stand atop regulation-height, 10-inch mounds to wind up. Then they’ll stride, cock their arms, accelerate, decelerate and follow through to release a ball that can reach speeds of 100 mph. Now, a motion analysis study of 20 elite pitchers from the major leagues and NCAA Division I-A college teams suggests that a 10-inch mound, also standard for high school ….. (FL) – March 29, 2008 ALLERGY DRUG RISK FAR FROM CERTAIN Patients with asthma and allergies called doctors across Tampa Bay Friday, worried as Singulair became the latest blockbuster drug hit by safety questions. But right now, the biggest safety threat is that asthma patients might stop the drug without talking to their physicians first, some bay area doctors said Friday. “What I would not want to see is somebody having a flare-up with their asthma and ending up in the E. R. because of (worry about) an event that’s ….. Montgomery Advertiser (AL) – March 29, 2008 FDA looks into Singulair The Food and Drug Administration is investigating anecdotal reports that people who use Singulair, the popular asthma and allergy drug, are at greater risk for suicidal thoughts and suicide. Singulair is a pill prescribed to treat asthma and hay fever symptoms. It blocks an inflammation pathway in the body that can cause both asthma and allergy symptoms. It was approved for treating asthma in 1998, and to treat seasonal allergy symptoms in 2003. In the past year, drugmaker Merck, of ….. – March 28, 2008 FDA investigates possible link between drug, suicide MATTHEW PERRONE AP Business Writer WASHINGTON (AP) – The Food and Drug Administration said Thursday it is investigating a possible link between Merck’s best-selling Singulair and suicide. FDA said it is reviewing reports of mood changes, suicidal behavior and suicide in patients who have taken the popular allergy drug. Merck has updated the drug’s labeling four times in the past year to include information on a range of side effects: tremors, anxiousness, ….. (CA) – March 28, 2008 Possible drug, suicide link probed, FDA looks into reports involving best-selling Singulair by Merck WASHINGTON – The Food and Drug Administration said Thursday that it is investigating a possible link between Merck’s best-selling Singulair and suicide. FDA said it is reviewing a handful of reports involving mood changes, suicidal behavior and suicide in patients who have taken the popular allergy and asthma drug. Merck has updated the drug’s labeling four times in the past year to include information on a range of reported side effects: tremors, anxiousness, ….. – March 28, 2008 Green Zone Lockdown: Diplomats Ordered Inside Suicide Link to the Drug Singulair? Sen. Bill Nelson’s Plan to Elect a President Dad Saves Son Who Fell in the Well KIRAN CHETRY, ANCHOR: Meanwhile, though, we have breaking news and rising tensions in Baghdad this morning. New moves from the prime minister of Iraq, Nuri al-Maliki. Iraq’s parliament convenes a special session this morning to address days of fighting that has been taking place between government troops and Shiite militias. U. S. diplomats in Baghdad are being warned to stay under cover until further notice after repeated rocket attacks into the Green Zone. Two U. S ….. 329. USA TODAY (Arlington, VA) – March 28, 2008 FDA looks into Singulair, risks of suicidal thoughts, Anecdotal reports from doctors, patients studied The Food and Drug Administration is investigating anecdotal reports that people who use Singulair, the popular asthma and allergy drug, are at greater risk for suicidal thoughts and suicide. Singulair is a pill prescribed to treat asthma and hay fever symptoms such as sneezing and a nose that is stuffy, runny or itchy. It blocks an inflammation pathway in the body that can cause both asthma and allergy symptoms. It was approved for treating asthma in 1998 and to treat seasonal …. – March 28, 2008 ‘Marketplace’ Report: Singulair Suicide Link? MADELEINE BRAND, host: From N , this is Day to Day. Federal regulators are looking into possible safety problems with the widely used asthma drug Singulair. There have been anecdotal reports of a link between Singulair and suicidal behavior. The Food and Drug Administration says it is investigating three or four suicides. Marketplace’s Bob Moon is here now, and Bob, is the FDA saying consumers should immediately stop taking this drug until they’ve concluded ….

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