391. FD (FAIR DISCLOSURE) WIRE – April 30, 2003 Q1 2003 AstraZeneca PLC Earnings Conference Call – Final OPERATOR: Good day ladies and gentlemen and welcome to the AstraZeneca Q1 Results Conference Call. This call is being recorded. Today’s Question and Answer Session will be conducted electronically. If you would like to ask a question, please press the star or asterix key, followed by the digit ‘1′ on your touchtone phone. At this time I would like to turn the call over Mr. Ed Seage (ph) with AstraZeneca. Please go ahead sir. ED SEAGE, IR, ASTRAZENECA …. 2. – December 6, 2002 Cops 08 Births Hospitals release the names of only those patients who sign consent forms. Great River Medical Center Dec. 3 Jim and Julie Belger, Burlington, girl Arrests/citations Reports are taken directly from the daily logs of area law enforcement agencies. Some agencies do not differentiate between arrests and citations. Burlington Saturday 3:28 a. m. Riverfront at south railroad bridge. Bradley Smyth, 29, 812 Emmett St. : open burning. 2:46 a. m. 222 Hayes Court ….. 3. – October 17, 2002 BREATHMOBILE, BETTER MEDICATIONS BRING KIDS HOPE OF A NORMAL LIFE As a child, Margaret Huggins spent many afternoons by the living-room window, feeling as fragile as the pane of glass through which she gazed. She would have been on the other side of that window, joining her friends in games of tag or hide-and-seek, if not for her asthma, a disease that would steal her breath away when she wasn’t careful. Huggins, 32, remembers those days even now as she looks out another living-room window, this time to watch her 13-year-old daughter, …. 4. Herbert River Express (Australia) – October 8, 2002 Asthma is no joke IT’S often been said that laughter is the best medicine. But when it comes to the treatment of asthma that may not always be the case. In fact laughing may be counter productive for children with asthma. A University of NSW study published earlier this year showed that the physical action of laughing (not the emotion of mirth) could sometimes trigger an attack. However, there’s no need to take the fun out of your child’s life. The good news, according …. 5. (CA) – September 4, 2002 How to treat asthma Dear Dr. Gott: My son, 31, has suffered from asthma for years. He’s happily married and enjoys his pets, plants and dried flower arrangements — all of which aggravate his condition. Just how serious is this for his well-being? Dear Reader: It could be quite serious. Although I understand your concern about your son’s health, only he can choose which steps he can take to improve it. For some asthma patients, the disease is a life-threatening handicap requiring aggressive …. 6. (CA) – September 4, 2002 How to treat asthma Dear Dr. Gott: My son, 31, has suffered from asthma for years. He’s happily married and enjoys his pets, plants and dried flower arrangements — all of which aggravate his condition. Just how serious is this for his well-being? Dear Reader: It could be quite serious. Although I understand your concern about your son’s health, only he can choose which steps he can take to improve it. For some asthma patients, the disease is a life-threatening handicap requiring aggressive …. 7. – September 4, 2002 How to treat asthma Dear Dr. Gott: My son, 31, has suffered from asthma for years. He’s happily married and enjoys his pets, plants and dried flower arrangements — all of which aggravate his condition. Just how serious is this for his well-being? Dear Reader: It could be quite serious. Although I understand your concern about your son’s health, only he can choose which steps he can take to improve it. For some asthma patients, the disease is a life-threatening handicap requiring aggressive …. 8. – September 4, 2002 How to treat asthma Dear Dr. Gott: My son, 31, has suffered from asthma for years. He’s happily married and enjoys his pets, plants and dried flower arrangements — all of which aggravate his condition. Just how serious is this for his well-being? Dear Reader: It could be quite serious. Although I understand your concern about your son’s health, only he can choose which steps he can take to improve it. For some asthma patients, the disease is a life-threatening handicap requiring aggressive …. 9. – September 4, 2002 How to treat asthma Dear Dr. Gott: My son, 31, has suffered from asthma for years. He’s happily married and enjoys his pets, plants and dried flower arrangements — all of which aggravate his condition. Just how serious is this for his well-being? Dear Reader: It could be quite serious. Although I understand your concern about your son’s health, only he can choose which steps he can take to improve it. For some asthma patients, the disease is a life-threatening handicap requiring aggressive ….. (FL) – May 18, 2002 EXERCISE-FREE METHOD OF BUILDING MUSCLE IN THE WORKS Wouldn’t it be nice to spend your evenings watching TV or reading and still build fit muscles? That fantasy may one day be a reality, thanks to the recent discovery in animal studies that muscle fibers can be transformed without exercise into the oxygen-burning, energizing type that are the pride of marathon runners. For about 10 years, scientists have been studying the chemical signals that turn muscle fibers that tire easily into fatigue-resistant ones. One signal that ….

361. – April 4, 2006 PREDNISONE ONLY ONE OF MANY ASTHMA DRUGS DEAR DR. DONOHUE: My wife has had asthma since 1998. She weighed 130 pounds then. She has been on prednisone for a few years, and her weight has gone up to 174 and it is all in her middle. Is there anything besides prednisone that would work for her? — M. D. ANSWER: Asthma makes people’s airways (bronchi) very sensitive to the slightest irritation. If they breathe things that wouldn’t bother the rest of us, their airways constrict, and that makes the passage of ….. Gazette, The (Cedar Rapids-Iowa City, IA) – April 4, 2006 Weight gain among side effects associated with prednisone Dear Dr. Donohue: My wife has had asthma since 1998. She weighed 130 pounds then. She has been on prednisone for a few years, and her weight has gone up to 174 and it is all in her middle. Is there anything besides prednisone that would work for her? – M. D. Answer: Asthma makes people’s airways (bronchi) very sensitive to the slightest irritation. If they breathe things that wouldn’t bother the rest of us, their airways constrict, and that makes the passage of air ….. (FL) – April 4, 2006 PREDNISONE ONLY ONE OF MANY ASTHMA DRUGS DEAR DR. DONOHUE: My wife has had asthma since 1998. She weighed 130 pounds then. She has been on prednisone for a few years, and her weight has gone up to 174 and it is all in her middle. Is there anything besides prednisone that would work for her? — M. D. ANSWER: Asthma makes people’s airways (bronchi) very sensitive to the slightest irritation. If they breathe things that wouldn’t bother the rest of us, their airways constrict, and that makes the passage of ….. – April 4, 2006 PREDNISONE ONLY ONE OF MANY ASTHMA DRUGS DEAR DR. DONOHUE: My wife has had asthma since 1998. She weighed 130 pounds then. She has been on prednisone for a few years, and her weight has gone up to 174 and it is all in her middle. Is there anything besides prednisone that would work for her? — M. D. ANSWER: Asthma makes people’s airways (bronchi) very sensitive to the slightest irritation. If they breathe things that wouldn’t bother the rest of us, their airways constrict, and that makes the passage of ….. – December 24, 2005 ASTHMA DOESN’T SIDELINE EASY ALAMEDA — These days, Omar Easy spends his Sundays chasing kick returners and trying to block punts for the Raiders’ special teams. When he was growing up in Saint Catherine, Jamaica, near the historic colonial site of Spanish Town, Sunday was all about church and soccer. Easy’s grandfather was a pastor, his grandmother a missionary, so it’s no surprise he spent every Sunday morning in church. The rest of the day was devoted to the first sport Easy knew ….. – December 24, 2005 ASTHMA DOESN’T SIDELINE EASY ALAMEDA — These days, Omar Easy spends his Sundays chasing kick returners and trying to block punts for the Raiders’ special teams. When he was growing up in Saint Catherine, Jamaica, near the historic colonial site of Spanish Town, Sunday was all about church and soccer. Easy’s grandfather was a pastor, his grandmother a missionary, so it’s no surprise he spent every Sunday morning in church. The rest of the day was devoted to the first sport Easy knew ….. wire (USA) – November 17, 2005 AstraZeneca Provides Additional Support to Hurricane Victims, Company launches relief efforts in partnership with Rotary Club of Houston to pledge additional support at AHA annual meeting PRNewswire-FirstCall — AstraZeneca (NYSE: AZN), one of the world’s leading pharmaceutical companies, announced today that it will provide an additional $125, 000 worth of critical supplies to hurricane victims. In partnership with the Rotary Club of Houston, AstraZeneca delivered two truckloads of critical supplies to El Centro de Corazon Health Clinic and El Spiritu de Salud Mobile Unit, which serve at-risk and underserved communities in the Houston area, including many families ….. – August 12, 2005 CAUSE OF CHRONIC HIVES OFTEN NOT FOUND DEAR DR. DONOHUE: I have had hives for almost three years. They pop up anywhere on my body. Sometimes my hands swell, too. I have seen a dermatologist, an allergist and a rheumatologist. Nothing has worked so far. Do you have any ideas? — D. F. ANSWER: Allergies, medicines such as ACE inhibitors and anti-inflammatory drugs, thyroid-gland disorders, parasite infections and illnesses like lupus are some of the hidden causes of recurrent crops of hives. You have seen three specialists, all ….. – August 12, 2005 CAUSE OF CHRONIC HIVES OFTEN NOT FOUND DEAR DR. DONOHUE: I have had hives for almost three years. They pop up anywhere on my body. Sometimes my hands swell, too. I have seen a dermatologist, an allergist and a rheumatologist. Nothing has worked so far. Do you have any ideas? — D. F. ANSWER: Allergies, medicines such as ACE inhibitors and anti-inflammatory drugs, thyroid-gland disorders, parasite infections and illnesses like lupus are some of the hidden causes of recurrent crops of hives. You have seen three specialists, all ….. (FL) – August 12, 2005 CAUSE OF CHRONIC HIVES OFTEN NOT FOUND DEAR DR. DONOHUE: I have had hives for almost three years. They pop up anywhere on my body. Sometimes my hands swell, too. I have seen a dermatologist, an allergist and a rheumatologist. Nothing has worked so far. Do you have any ideas? — D. F. ANSWER: Allergies, medicines such as ACE inhibitors and anti-inflammatory drugs, thyroid-gland disorders, parasite infections and illnesses like lupus are some of the hidden causes of recurrent crops of hives. You have seen three specialists, all ….

381. – December 15, 2004 Drug Induced Liver Injury Expected to Increase with Almost Half of All Americans Now Using Prescription Drugs HepaLife Technologies, Inc. Ms. Sarah H. Simpson, 800-518-4879 www. HepaLife. com HepaLife Technologies, Inc. (OTCBB:HPLF), a development stage biotechnology company focused on the research, development and eventual commercialization of technologies and products for liver toxicity detection and the treatment of various forms of liver dysfunction and disease, today announces its expectations of increased drug induced liver injuries and adverse drug reactions due to a dramatic rise in ….. Honolulu Advertiser, The (HI) – May 8, 2004 Prescriptions By Landis Lum Inhaled steroids crucial for asthma Q. Both my son and I have asthma, and my doctor wants us to use a steroid inhaler every day, even when we’re not wheezing. What gives? Not only does it not work as fast as quick-relief inhalers like Albuterol, Alupent, or Maxair, but aren’t steroids bad? If you or your child awakens three or more nights a month because of coughing or wheezing, or needs to use a quick-relief medication like albuterol inhaler ….. Financial Times (London, England) – April 20, 2004 All eyes on stores as bid speculation takes hold Retail stocks were the centre of attention in the London equity market yesterday on bid speculation which, in the case of Marks and Spencer, lost some momentum by the close of trading. M&S rose as high as 280p following weekend reports that US equity firm Kohlberg Kravis Roberts and UK retail entrepreneur Philip Green were interested in buying the struggling retailer, however it finally ended just 4. 9 per cent higher at 277{1/2}p. KKR’s attention appeared to be ….. Times, The (London, England) – April 20, 2004 Rival’s problems provide a boost for mmO2, Larger capitalisation shares THE takeover ambitions of KPN towards mmO2 were cast in a new light yesterday after it emerged that the success of the UK mobile operator in the German market had prompted belt-tightening at the Dutch carrier’s E-Plus subsidiary. Following KPN’s admission of a takeover approach for mmO2 in February, thought to have been pitched at 108p a share, the Dutch group’s insistence that it had no current plans to revisit its bid has forced shareholders of the ….. Washington Post – February 24, 2004 Dialing for Drugs A Weekly Check on Health Care Costs and Coverage Carolyn Odio of Herndon doesn’t know why it was so hard to get a prescription filled for her son, but she’s sure “there was a lot of miscommunication going on. ” On Dec. 24, she wrote in a letter of complaint, psychiatrist Peter Robbins prescribed Concerta for her son. At the pharmacy, however, she was told MAMSI would not help pay for the ADHD drug unless Robbins got prior authorization from the insurer. On Dec. 26, Odio added, ….. (CA) – December 25, 2003 Q&A DEAR STEVE: One of our two cats has fleas really bad. If you rub her, it feels like there are bumps all over her skin. We’ve soaked her with flea spray and tried a flea collar but they haven’t helped. How can I economically deal with these pests? –L. B. , Charlotte, N. C. Steve Dale ANSWER: Michael Dryden, a veterinary parasitologist at Kansas State University College of Veterinary Medicine, says it’s no surprise the over-the-counter products ….. (KS) – December 22, 2003 B Cat’s extreme flea problem calls for serious action Question: One of our two cats has fleas really bad. If you rub her, it feels like there are bumps all over her skin. We have soaked her with flea spray and tried a flea collar but they haven’t helped. How can I economically deal with these pests? — L. B. , Charlotte, N. C. Answer: Dr. Michael Dryden, a veterinary parasitologist at Kansas State University College of Veterinary Medicine in Manhattan, Kan. , says it …. Clay County Advocate-Press, The (Flora, IL) – June 25, 2003 Everyone seeks relief from allergies Summer is the season of when nearly everyone wants to be outdoors enjoying the warm weather and sunshine. But for many people this season brings sneezing, wheezing, watery eyes, and runny noses – all allergic reactions for many individuals. “Allergic symptoms are caused by the immune system overreacting to harmless substances called allergens, which create irritation and inflammation of the lining of the upper airway, ” said Dr. Akshay Sood, assistant professor of …. Herbert River Express (Australia) – May 6, 2003 Asthma treatments THIS year World Asthma Day (May 7) has focused our attention on the need for everyone with asthma to recognise the severity of their symptoms and to understand what are the most effective treatments for them personally. It has been estimated that more than two million people in Australia have asthma, and this number is increasing. There is an enormous cost, therefore, to our community both in terms of quality of life and in financial terms. The disease costs us about $700 million per …. 0. FD (FAIR DISCLOSURE) WIRE – April 30, 2003 Event Brief of Q1 2003 AstraZeneca PLC Earnings Conference Call – Final CORPORATE PARTICIPANTS. Ed Seage, AstraZeneca PLC, IR. Jon Symonds, AstraZeneca PLC, CFO & Director. Mike Anse, AstraZeneca PLC, Corporate Affairs OVERVIEW AZN reported 1Q03 sales in constant currency were up 4% to $4. 7b, with EPS down 3% to $0. 54. The pace of transformation saw AZN able to absorb almost $700m of generic erosion in the US in the quarter. US pharmaceutical sales were up 3%, with generic erosion in some brands more than offset by 55% growth in the ….

371. (FL) – August 12, 2005 CAUSE OF CHRONIC HIVES OFTEN NOT FOUND DEAR DR. DONOHUE: I have had hives for almost three years. They pop up anywhere on my body. Sometimes my hands swell, too. I have seen a dermatologist, an allergist and a rheumatologist. Nothing has worked so far. Do you have any ideas? — D. F. ANSWER: Allergies, medicines such as ACE inhibitors and anti-inflammatory drugs, thyroid-gland disorders, parasite infections and illnesses like lupus are some of the hidden causes of recurrent crops of hives. You have seen three specialists, all ….. (FL) – August 12, 2005 CAUSE OF CHRONIC HIVES OFTEN NOT FOUND DEAR DR. DONOHUE: I have had hives for almost three years. They pop up anywhere on my body. Sometimes my hands swell, too. I have seen a dermatologist, an allergist and a rheumatologist. Nothing has worked so far. Do you have any ideas? — D. F. ANSWER: Allergies, medicines such as ACE inhibitors and anti-inflammatory drugs, thyroid-gland disorders, parasite infections and illnesses like lupus are some of the hidden causes of recurrent crops of hives. You have seen three specialists, all ….. (NY) – August 12, 2005 CAUSE OF HIVES MIGHT NOT BE FOUND Dear Dr. Donohue: I have had hives for almost three years. They pop up anywhere on my body. Sometimes my hands swell, too. I have seen a dermatologist, an allergist and a rheumatologist. Nothing has worked so far. Do you have any ideas? – D. F. Allergies, medicines such as ACE inhibitors and anti-inflammatory drugs, thyroid-gland disorders, parasite infections and illnesses like lupus are some of the hidden causes of recurrent crops of hives. You have seen three specialists, all of whom ….. South Florida Sun-Sentinel (Fort Lauderdale, FL) – June 5, 2005 DR. PAUL DONOHUE GOOD HEALTH Dear Dr. Donohue: My 17-year-old son was just diagnosed with asthma. I am very confused by the medicines he takes. Would you please explain asthma medicines and how they’re used? — K. K. Dear K. K. : Asthma is a sudden constriction of airways together with an overproduction of mucus in those air passages. That makes it difficult to get air into and out of the lungs. An attack is much like being choked. I can simplify the concept of the two kinds of asthma medicines. One kind ….. (NY) – June 5, 2005 ASTHMA MEDICINES TAKE 2 DIFFERENT APPROACHES Dear Dr. Donohue: My 17-year-old son has just been diagnosed as having asthma. I am very confused by the medicines he takes. Would you please explain, in as simple terms as possible, asthma medicines and how they’re used? – K. K. Asthma is a sudden constriction of airways together with an overproduction of mucus in those air passages. That makes it difficult to get air into and out of the lungs. An attack is much like being choked. I can’t mention all asthma ….. – April 16, 2005 PHILADELPHIA — The recommendation that adults with mild asthma take medication every day to control the disease might be unnecessary, a new study suggests. Patients with mild persistent asthma who went without inhaled steroids or other daily medication had no more frequent asthma flare-ups than and had equally good lung function as patients who used the drugs. The study calls into question treatment guidelines issued in 1997 by a federal panel that recommend daily medication PHILADELPHIA — The recommendation that adults with mild asthma take medication every day to control the disease might be unnecessary, a new study suggests. Patients with mild persistent asthma who went without inhaled steroids or other daily medication had no more frequent asthma flare-ups than and had equally good lung function as patients who used the drugs. The study calls into question treatment guidelines issued in 1997 by a federal panel that recommend daily medication ….. Los Angeles Times (CA) – April 14, 2005 The Nation Adults With Mild Asthma Can Limit Drugs, Study Says About 4 million adult Americans with a mild form of asthma may not need to take daily steroid doses, but instead can use the drug only as needed to control symptoms, says a new study supported by the National Institutes of Health. The change would make drug use more convenient, minimize side effects from the powerful drugs and possibly save the nation as much as $2 billion per year, the study concludes. Its results do not apply to the 10 million adults with more severe forms of the …. – April 14, 2005 Asthma drug routine challenged Research suggests people with mild cases use medication when their symptoms flare up Doctors tell asthma patients to take their preventive medications daily, even if they feel fine. Physicians believe this routine can avert attacks and keep lungs healthier. But a new study challenges these widely accepted guidelines – at least for people with mild asthma. Research published in today’s New England Journal of Medicine found that people with mild, persistent asthma did very well simply by keeping their medications on hand and using the drugs only ….. (NY) – April 3, 2005 ALLERGIES MAY PLAY ROLE IN ASTHMA AT NIGHTTIME Dear Dr. Donohue: I have suffered from severe allergies and severe asthma since childhood. I take Advair, but it has had no noticeable effect on my nocturnal asthma, which is my main concern. Do you know any treatments that can ease nocturnal asthma? – D. R. Asthma is recurrent episodes of breathlessness, wheezing, chest tightness and coughing due to a sudden narrowing of the airways. Asthma attacks often strike during the night, and the reasons why aren’t clear. Your first ….. Birmingham Post, The (England) – February 16, 2005 The Birmingham Post: CULTURE: Amateur Stage: Is Ayckbourn losing his grip on English grammar? The one thing of which you can usually be certain in the shifting, unpredictable world of theatre is that another Alan Ayckbourn play is on the way. I don’t mean another via the local drama group, although it is hardly unusual to find one of them is about to offer its own account of something from the abundance of Ayckbourns at the disposal of amateurs. Indeed, Henley-in-Arden Dramatic Society opens with It Could Be Any One of Us tonight. No, I mean another – yet another, ….

411. – March 13, 2002 Ask Dr. Gott Little things mean lot to asthmatics Q. My son, 31, has suffered from asthma for years. He’s happily married and enjoys his pets, plants and dried flower arrangements — all of which aggravate his condition. Just how serious is this for his well-being? A. It could be quite serious. Although I understand your concern about your son’s health, only he can choose which steps he can take to improve it. For some asthma patients, the disease is a life-threatening handicap requiring aggressive ….. (PA) – March 13, 2002 Environmental factors can worsen asthma QMy son, 31, has suffered from asthma for years. He’s happily married and enjoys his pets, plants and dried flower arrangements — all of which aggravate his condition. Just how serious is this for his well-being? AIt could be quite serious. Although I understand your concern about your son’s health, only he can choose which steps he can take to improve it. For some asthma patients, the disease is a life-threatening handicap requiring aggressive ….. Times, The (Trenton, NJ) – November 15, 2001 Exercise-induced asthma is treatable DEAR DR. GOTT: I have been diagnosed with exercise-induced asthma. What is this disorder? Can it be fatal? DEAR READER: Asthma can be fatal. In fact, specialists are concerned about the increasing number of unnecessary deaths nationwide due to this common lung condition. Asthma is a chronic, cyclic pulmonary disorder, marked by excess mucus secretions and bronchospasm, narrowing of the breathing passages. This impairs respiration and leads to wheezing, coughing, breathlessness and — in ….. (PA) – November 15, 2001 Exercise-induced asthma treatable with medication QI have been diagnosed with exercise-induced asthma. What is this disorder? Can it be fatal? AAsthma can be fatal. In fact, specialists are concerned about the increasing number of unnecessary deaths nationwide due to this common lung condition. Asthma is a chronic, cyclic pulmonary disorder, marked by excess mucus secretions and bronchospasm, narrowing of the breathing passages. This impairs respiration and leads to wheezing, coughing, breathlessness and — in severe cases ….. – November 15, 2001 Ask Dr. Gott Exercise-induced asthma is treatable Q: I have been diagnosed with exercise-induced asthma. What is this disorder? Can it be fatal? A: Asthma can be fatal. In fact, specialists are concerned about the increasing number of unnecessary deaths nationwide due to this common lung condition. Asthma is a chronic, cyclic pulmonary disorder, marked by excess mucus secretions and bronchospasm, narrowing of the breathing passages. This impairs respiration and leads to wheezing, coughing, breathlessness and — in severe ….. – November 15, 2001 Ask Dr. Gott Exercise-induced asthma is treatable Q: I have been diagnosed with exercise-induced asthma. What is this disorder? Can it be fatal? A: Asthma can be fatal. In fact, specialists are concerned about the increasing number of unnecessary deaths nationwide due to this common lung condition. Asthma is a chronic, cyclic pulmonary disorder, marked by excess mucus secretions and bronchospasm, narrowing of the breathing passages. This impairs respiration and leads to wheezing, coughing, breathlessness and — in severe ….. Star (NE) – November 15, 2001 Exercise-induced asthma can be treated Dear Dr. Gott: I have been diagnosed with exercise-induced asthma. What is this disorder? Can it be fatal? Dear Reader: Asthma can be fatal. In fact, specialists are concerned about the increasing number of unnecessary deaths nationwide due to this common lung condition. Asthma is a chronic, cyclic pulmonary disorder, marked by excess mucus secretions and bronchospasm, narrowing of the breathing passages. This impairs respiration and leads to wheezing, coughing, breathlessness and ….. Times=City – July 20, 2001 Asthma outpaces medicine Rates have skyrocketed in last two decades By Amy Mercer The Times For millions of people, the lost city of Atlantis is a reality. They struggle for breath and, as if living in a city under the sea, they can’t seem to catch it. But the most breathtaking news of all is, despite advances in medical science, physicians have been unable to stop the increasing prevalence of asthma, a chronic condition that affects 16 million Americans. In the last two decades, ….. (CA) – June 2, 2001 ASTHMA EDUCATION IS THE BEST DEFENSE Asthma is a lung disease that affects more than 14 million Americans, and is responsible for more than 5, 000 deaths annually. It is important to take asthma seriously because, although for many people it is a chronic condition, a good understanding of the disease and awareness of the prevention and treatment available are the keys to taking control of it. Asthma occurs due to inflammation of the airways as a result of certain triggers. These can include a simple cold or viral and bacterial …. (CA) – June 2, 2001 ASTHMA EDUCATION IS THE BEST DEFENSE Asthma is a lung disease that affects more than 14 million Americans, and is responsible for more than 5, 000 deaths annually. It is important to take asthma seriously because, although for many people it is a chronic condition, a good understanding of the disease and awareness of the prevention and treatment available are the keys to taking control of it. Asthma occurs due to inflammation of the airways as a result of certain triggers. These can include a simple cold or viral and bacterial ….

401. (FL) – May 18, 2002 EXERCISE-FREE METHOD OF BUILDING MUSCLE IN THE WORKS Wouldn’t it be nice to spend your evenings watching TV or reading and still build fit muscles? That fantasy may one day be a reality, thanks to the recent discovery in animal studies that muscle fibers can be transformed without exercise into the oxygen-burning, energizing type that are the pride of marathon runners. For about 10 years, scientists have been studying the chemical signals that turn muscle fibers that tire easily into fatigue-resistant ones. One signal that ….. – May 18, 2002 EXERCISE-FREE METHOD OF BUILDING MUSCLE IN THE WORKS Wouldn’t it be nice to spend your evenings watching TV or reading and still build fit muscles? That fantasy may one day be a reality, thanks to the recent discovery in animal studies that muscle fibers can be transformed without exercise into the oxygen-burning, energizing type that are the pride of marathon runners. For about 10 years, scientists have been studying the chemical signals that turn muscle fibers that tire easily into fatigue-resistant ones. One signal that ….. (FL) – May 18, 2002 EXERCISE-FREE METHOD OF BUILDING MUSCLE IN THE WORKS Wouldn’t it be nice to spend your evenings watching TV or reading and still build fit muscles? That fantasy may one day be a reality, thanks to the recent discovery in animal studies that muscle fibers can be transformed without exercise into the oxygen-burning, energizing type that are the pride of marathon runners. For about 10 years, scientists have been studying the chemical signals that turn muscle fibers that tire easily into fatigue-resistant ones. One signal that ….. – May 18, 2002 EXERCISE-FREE METHOD OF BUILDING MUSCLE IN THE WORKS Wouldn’t it be nice to spend your evenings watching TV or reading and still build fit muscles? That fantasy may one day be a reality, thanks to the recent discovery in animal studies that muscle fibers can be transformed without exercise into the oxygen-burning, energizing type that are the pride of marathon runners. For about 10 years, scientists have been studying the chemical signals that turn muscle fibers that tire easily into fatigue-resistant ones. One signal that ….. Los Angeles Times – April 29, 2002 Capsules Delaying Breast Biopsy May Be a Poor Strategy When a mammogram reveals a highly suspicious area, a biopsy is done quickly to determine if it’s malignant. But when there’s a subtle abnormality, the doctor may say, “Come back in six months and we’ll take another look. ” If it is cancer, that six months may be too long to wait. A study of 4, 465 Canadian women with breast cancer found that delaying diagnosis for more than 20 weeks after abnormal screening tests worsens prognostic ….. (PA) – April 11, 2002 Sinus lavage might be alternative to surgery Q I’m 68 and in good health. However, for the past few months, I’ve had balance problems; I sometimes stagger when I walk and frequently experience unsteadiness. In the process of investigating this symptom, my otolaryngologist performed a CT scan and was surprised to discover that I have a serious infection in two of my sinuses. He feels that the irritation is somehow affecting my inner ear, which throws off my balance. He gave me a two-month course of antibiotics ….. Times, The (Trenton, NJ) – April 11, 2002 Is sinus lavage out of style? DEAR DR. GOTT: I’m 68 and in good health. However, for the past few months, I’ve had balance problems; I sometimes stagger when I walk and frequently experience unsteadiness. In the process of investigating this symptom, my otolaryngologist performed a CT scan and was surprised to discover that I have a serious infection in two of my sinuses. He feels that the irritation is somehow affecting my inner ear, which throws off my balance. He gave me a two- month course of ….. – March 13, 2002 Ask Dr. Gott Little things mean lot to asthmatics Q. My son, 31, has suffered from asthma for years. He’s happily married and enjoys his pets, plants and dried flower arrangements — all of which aggravate his condition. Just how serious is this for his well-being? A. It could be quite serious. Although I understand your concern about your son’s health, only he can choose which steps he can take to improve it. For some asthma patients, the disease is a life-threatening handicap requiring aggressive ….. (FL) – March 13, 2002 How serious is son’s long-term asthma condition? DEAR DR. GOTT: My son, 31, has suffered from asthma for years. He’s happily married and enjoys his pets, plants and dried flower arrangements — all of which aggravate his condition. Just how serious is this for his wellbeing? DEAR READER: It could be quite serious. Although I understand your concern about your son’s health, only he can choose which steps he can take to improve it. For some asthma patients, the disease is a life-threatening handicap requiring …. Times, The (Trenton, NJ) – March 13, 2002 How to treat asthma DEAR DR. GOTT: My son, 31, has suffered from asthma for years. He’s happily married and enjoys his pets, plants and dried flower arrangements — all of which aggravate his condition. Just how serious is this for his well-being? DEAR READER: It could be quite serious. Although I understand your concern about your son’s health, only he can choose which steps he can take to improve it. For some asthma patients, the disease is a life-threatening handicap requiring ….

431. – February 25, 2001 Allergy and Asthma Clinic improves life’s quality For many people the advent of spring means sneezes, runny noses, itching eyes, and worse. Allergy and asthma sufferers often see an increase in their symptoms as the growing season arrives. With new treatment options, it doesn’t have to be the case. You can greet spring without all the annoying symptoms of allergies and asthma. You don’t have to suffer any longer, says Dr. Ted Kanellakes of the Allergy and Asthma Clinic, 229 N. Hammes in Joliet and 23959 ….. (NJ) – February 21, 2001 RESEARCH SHOWS PROMISE FOR NEW ASTHMA VACCINE In a sprawling lab just down the hall from his office, Dr. Shyam Mohapatra and his team tweak tiny genes in hopes of making big changes. With asthma cases spiking since 1980 and no end in sight, many researchers believe their best chance for stemming the disease is a vaccine based on gene therapy. Asthma and allergies are caused by immune system disorders. At the University of South Florida, Mohapatra and other researchers are trying to devise a vaccine that would force the immune ….. – February 11, 2001 USF research shows promise for asthma vaccine The college’s team is breaking down the factors that contribute to the condition. In a sprawling lab just down the hall from his office, Dr. Shyam S. Mohapatra and his team tweak tiny genes in hopes of making big changes. With asthma cases spiking since 1980 and no end in sight, many researchers believe their best chance for stemming the disease is a vaccine based on gene therapy. Asthma and allergies are caused by immune system disorders. At the University of South ….. Evening Standard, The (London, England) – December 14, 2000 Barclays In Spotlight With L&g Link Buzz: MARKET REPORT Barclays In Spotlight With L&g Link Buzz: MARKET REPORT AS LLOYDS TSB continues to ponder whether to launch an aggressive bid for rival Abbey National, speculation within the Square Mile claims Barclays is putting the finishing touches to an agreed merger with life assurer Legal & General. Word is the two sides have been holding top-level talks for several months. If such a deal is concluded, it would create a financial services empire worth more ….. KNIGHT RIDDER/TRIBUNE BUSINESS NEWS – December 14, 2000 BANK STOCKS LEAD TRADING ON BULLY DAY FOR BRITISH MARKETS Dec. 14–As Lloyds TSB continues to ponder whether to launch an aggressive bid for rival Abbey National, speculation within the Square Mile claims Barclays is putting the finishing touches to an agreed merger with life assurer Legal & General. Word is the two sides have been holding top-level talks for several months. If such a deal is concluded, it would create a financial services empire worth more than UKpound 45 billion. Today shares of Legal & General were 21/4 ….. Evening Standard, The (London, England) – December 14, 2000 Barclays In Spotlight With L&g Link Buzz: MARKET REPORT Barclays In Spotlight With L&g Link Buzz: MARKET REPORT AS LLOYDS TSB continues to ponder whether to launch an aggressive bid for rival Abbey National, speculation within the Square Mile claims Barclays is putting the finishing touches to an agreed merger with life assurer Legal & General. Word is the two sides have been holding top-level talks for several months. If such a deal is concluded, it would create a financial services empire worth more ….. Evening Standard, The (London, England) – December 14, 2000 Barclays In Spotlight With L&g Link Buzz: MARKET REPORT AS LLOYDS TSB continues to ponder whether to launch an aggressive bid for rival Abbey National, speculation within the Square Mile claims Barclays is putting the finishing touches to an agreed merger with life assurer Legal & General. Word is the two sides have been holding top-level talks for several months. If such a deal is concluded, it would create a financial services empire worth more than Pounds 45 billion. Today shares of Legal & General were ….. Evening Standard, The (London, England) – December 14, 2000 Barclays In Spotlight With L&g Link Buzz: MARKET REPORT WALL STREET was chased lower by the Chase Manhattan profits warning. The Dow was off 166. 75 points at 10, 627. 69 while the Nasdaq fell 54. 83 to 2767. 94. AS Lloyds TSB continues to ponder whether to launch an aggressive bid for rival Abbey National, speculation within the Square Mile claims Barclays is putting the finishing touches to an agreed merger with life assurer Legal & General. Word is the two sides have been holding top-level talks for several ….. Evening Standard, The (London, England) – December 14, 2000 Barclays In Spotlight With L&g Link Buzz: MARKET REPORT WALL STREET was chased lower by the Chase Manhattan profits warning. The Dow was off 166. 75 points at 10, 627. 69 while the Nasdaq fell 54. 83 to 2767. 94. AS Lloyds TSB continues to ponder whether to launch an aggressive bid for rival Abbey National, speculation within the Square Mile claims Barclays is putting the finishing touches to an agreed merger with life assurer Legal & General. Word is the two sides have been holding top-level talks for several ….. – November 14, 2000 Breathe easier with proper asthma information FAMILY MEDICINE Q. I am 27 years old and was diagnosed with asthma when I was 7. My symptoms have improved over the years. When I develop chest tightness or wheezing, usually about two or three times per week, I use an albuterol inhaler and I feel better. If I use albuterol more frequently, I develop palpitations. With all the new medicines available to treat asthma, is albuterol the best medicine for me? A. Asthma is a serious disorder characterized by chronic inflammation of the ….

421. Opinion, La (Los Angeles, CA) – May 23, 2001 Novedades médicas Las alergias y la lana De acuerdo con un estudio publicado en la revista médica Journal of Allergy and Clinical Immunology, si padece de alergias y de síntomas como estornudos debidos a éstas, evite usar ropa de lana. Los investigadores de la Universidad de Sydney, Australia, encontraron que usar un suéter de lana, aumenta 10 veces la exposición a ciertos organismos como los ácaros (mites), y aumenta la exposición a los productos de la piel del gato que causan alergias. Ellos ….. Washington Post – May 8, 2001 Pollen Counts Set Records — at Allergists’ Offices A Good Spring for Trees Has Been a Breath Stopper for Asthmatics and Others Allergist Howard Boltansky is reluctant to call this year’s bumper crop of tree pollen a windfall. Still, he says, his office is “on pace for a new record. ” “This has been definitely one of the busiest springs we’ve ever seen, ” says Boltansky, who has offices in Washington and Rockville. “We’re getting a lot of calls from people who were able to tolerate past levels. Even people with ….. Times Union, The (Albany, NY) – April 17, 2001 THE SNEEZIN’ SEASONDRUGS, THERAPIES CAN PROVIDE RELIEF TO CHRONIC-ALLERGY SUFFERERS It’s spring, and you know your eyes will start itching and your nose will start dripping soon. It’s hay fever time — misery time — just like every year. But do you know why your body isn’t fond of pollen? Or what allergy drugs are on the horizon? Didn’t think so. You’re definitely not alone. When the asked readers to send in questions about seasonal allergies and what to do about them, they were ….. (NY) – April 15, 2001 ALLERGY PILLS NOT TO BE SNEEZED AT Here’s a look at some of the most popular allergy drugs currently on the market, and what medical experts say about them: Over the counter: * Antihistamine tablets and liquids like Benadryl, Dimetapp and Chlor-Trimeton. These drugs effectively block the production of histamine, the body chemical that causes hives, itching and nasal congestion, but they result in drowsiness and slowed reactions. “Studies show they impair your driving ability more than ….. Sun Herald, The (Biloxi, MS) – April 2, 2001 SPRING MISERY, ALLERGIES ABOUND WHEN NATURE BLOOMS< > TEXT: > It’s spring, and you know your eyes will start itching and your nose will start dripping soon. It’s hay fever time — misery time — just like every year. But do you know why your body isn’t fond of pollen? Or what allergy drugs are on the horizon? Didn’t think so. You’re definitely not alone. But what do you really know about allergies? Here’s a primer: Q: ….. – March 29, 2001 Spring is here, so allergies can’t be far behind It’s spring, and you know your eyes will start itching and your nose will start dripping soon. It’s hay fever time — misery time — just like every year. But do you know why your body isn’t fond of pollen? Or what allergy drugs are on the horizon? Didn’t think so. We turned to experts for some answers. Perfect reading for when you’re stuck in your allergist’s waiting room. Q ….. . (Walnut Creek, CA) – March 27, 2001 KNOW YOUR ALLERGIES, EXPERTS ANSWER QUESTIONS ABOUT DREADED SCORGE OF SPRING It’s spring, and you know your eyes will start itching and your nose will start dripping soon. It’s hay-fever time misery time just like every year. But do you know why your body isn’t fond of pollen? Or what allergy drugs are on the horizon? Didn’t think so. You’re definitely not alone. When we asked readers to send in questions about seasonal allergies and what to do about them, we were inundated with letters, faxes ….. (CA) – March 20, 2001 ALL ABOUT ALLERGIES SEASONAL MISERY EXPLAINED WHY DO OUR NOSES GO HAYWIRE AND OTHER QUESTIONS FOR AN ALLERGIST It’s the first day of spring, and you know your eyes will start itching and your nose will start dripping soon. It’s hay fever time — misery time — just like every year. But do you know why your body isn’t fond of pollen? Or what allergy drugs are on the horizon? Didn’t think so. You’re definitely not alone. When we asked readers to send in questions about seasonal allergies and what to do about them, we were ….. (KS) – March 19, 2001 By WES ALLISON TAMPA, Fla. – In a sprawling lab just down the hall from his office, Dr. Shyam Mohapatra and his team tweak tiny genes in hopes of making big changes. With asthma cases spiking since 1980 and no end in sight, many researchers believe their best chance for stemming the disease is a vaccine based on gene therapy. Asthma and allergies are caused by immune system disorders. At the University of South Florida, Mohapatra and other researchers are trying to devise a ….. – March 1, 2001 INTRUDER MAKES LIFE CHAOTIC It’s Kody Hollaway’s 12th birthday, and his mother is in the kitchen making his favorite dinner of meatballs with rice and parsley. She’s mixing the meat and arguing with Elizabeth, 11, standing at her elbow, about just how short she can cut her hair. The twins, who just turned 9, are sparring in the garage, each wearing one big red boxing glove and shouting “hi-yah!”Destany, 10, is singing Que Sera Sera, spinning on the ….

441. Herbert River Express (Australia) – October 17, 2000 Fact cards make breathing easier This month pharmacies are focussing on asthma. During October, the nearly 1500 pharmacies around Australia with the Self Care information cards are providing information, not only on what asthma is and what the likely causes are, but also, even more importantly, on how to keep the condition under control. Asthma occurs at all ages; however, most people with asthma first experience symptoms in early childhood. In fact, 25 per cent of children under the age of five have asthma. It is the most ….. (MI) – June 13, 2000 DRIP, WHEEZE AND SNEEZE DOCTORS’ RENEWED INTEREST IN TREATING ALLERGIES OFFERS NEW HOPE TO SUFFERERS Sneezy, sleepy, dopey, grumpy? Better think about visiting Doc. Although hay fever has long been thought to be little more than a pain in the nose, health experts are now recommending that many allergy sufferers seek a physician’s care — and they’re encouraging family physicians to be more vigilant about diagnosing the condition. For decades, allergic disease has suffered from what many medical officials are calling a lack of respect, as patients — ….. Washington Post – June 6, 2000 Ask Your Doctor About …. Which of the Many Advertised Allergy Drugs Are Right for You? It’s hard not to have heard of Claritin, the world’s top-selling allergy drug and, with sales last year of more than $1. 5 billion, the eighth best-selling drug in the United States. After all, the maker of the non-sedating antihistamine, Schering-Plough, spent almost $140 million last year on television, radio, newspaper, magazine and billboard advertising, according to John F. Fezzuoglio, a marketing research analyst with the drug consulting firm Scott-Levin. In ….. (PA) – May 9, 2000 NO HEADLINE Carpal tunnel link? Women with large breasts are more likely to suffer from carpal tunnel syndrome than their smaller-breasted counterparts, according to a study headed by a Tuscaloosa, Ala. , plastic surgeon. But the symptoms of carpal tunnel — a malady that causes tingling in the hand and wrist pain often associated with heavy use of computer keyboards or other repetitious motions — cleared up after breast reduction surgery. Certain physical problems are more common among ….. El Norte (Monterrey, Nuevo León, Mexico) – 8 de mayo del 2000 Cita con el Doctor/ El asma: ¿Cómo controlarlo? El asma es una enfermedad crónica que hoy afecta al 2. 5 por ciento de la población aunque se espera que el número se cuadruplique durante los próximos años. Es la causa número uno de ausentismo escolar y laboral, y cada año se gastan hasta seis mil millones de dólares para tratar a los pacientes afectados por ella. Sin embargo, aún existe desconocimiento sobre este mal y por eso se decidió que el 3 de mayo, como el Día Mundial del Asma, sirviera como detonador para difundir …. 446. Washington Post – May 2, 2000 INTAKE Mouth Clicks Trying to eat responsibly and willing to spend time at your computer in order to do it? The Department of Agriculture has a new Web site for you. At the Interactive Healthy Eating Index on www. usda. gov/cnpp, you fill out a form detailing all the food you’ve consumed over the past 24 hours. (Presumably this includes the things you ate standing in front of the refrigerator at night when no one was looking. ) The site will quickly calculate how your reported ….. Family Life – May 1, 2000 Breathe Easy: Controlling Asthma and Allergies One night last fall, 9-year-old Marissa Lynn of Bow, NH, went to bed with a cold and awoke at 3 a. m. struggling for breath. Her parents gave her a dose of medicine from an inhaler that delivers medication in a mist to open up air passages. They had used the inhaler months before when Marissa had been diagnosed with an upper-respiratory infection. Only two hours later, Marissa needed the medicine again. By seven that morning, when her complaints still hadn’t eased, her parents took ….. (NY) – April 27, 2000 ALLERGY SEASON COMING ACHOO! Mild winter brings early return of tree pollen misery The season for sneezin’ has arrived early – and with a vengeance. A warm winter caused the pollinating to begin earlier than usual. The early pollen spurts, in turn, jump-started the nasty cycle of sensitization and misery for sufferers. Now that the weather is warming up, pollen counts have been “off the wall, ” said Dr. Leonard Bielory of the University of Medicine and Dentistry of New Jersey. “It’s 1, 100 for trees, extremely ….. (CT) – April 20, 2000 Allergies are nothing to sneeze at; If season makes you miserable, it may be time to see a doctor Sneezy, sleepy, dopey, grumpy? Better think about visiting Doc. Although hay fever has long been thought to be little more than a pain in the nose, health experts are now recommending that many allergy sufferers seek a physician’s care – and they’re encouraging family physicians to be more vigilant about diagnosing the condition. Allergic disease has suffered for decades from what many medical officials are calling a lack of respect, with patients – and ….. (GA) – April 18, 2000 NOTHING TO S N E E Z E AT Sneezy, sleepy, dopey, grumpy? Better think about visiting Doc. Although hay fever has long been thought to be little more than a pain in the nose, health experts are now recommending that many allergy sufferers seek a physician’s care — and they’re encouraging family physicians to be more vigilant about diagnosing the condition. Allergic disease has suffered for decades from what many medical officials are calling a lack of respect, with patients — and ….

451. – April 13, 2000 Allergy victims urged to get aid An Infobox appears at the bottom of this story. Sneezy, sleepy, dopey, grumpy? Better think about visiting Doc. Although hay fever has long been thought to be little more than a pain in the nose, health experts are now recommending that many allergy sufferers seek a physician’s care — and they’re encouraging family physicians to be more vigilant about diagnosing the condition. Allergic disease has suffered for decades from what many ….. , The (NC) – April 10, 2000 A NEW ATTACK ON ALLERGIES Sneezy, sleepy, dopey, grumpy? Better think about visiting Doc. Although hay fever has long been thought to be little more than a pain in the nose, health experts are now recommending that many allergy sufferers seek a physician’s care – and they’re encouraging family physicians to be more vigilant about diagnosing the condition. Allergic disease has suffered for decades from what many medical officials are calling a lack of respect, with patients – and ….. (WA) – April 9, 2000 Experts urge new emphasis in treating allergy suffering Although hay fever has long been thought to be little more than a pain in the nose, health experts are now recommending that many allergy sufferers seek a physician’s care – and they’re encouraging family physicians to be more vigilant about diagnosing the condition. Allergic disease has suffered for decades from what many medical officials are calling a lack of respect, with patients – and physicians themselves – failing to take the ailment seriously. Although ….. (Walnut Creek, CA) – March 28, 2000 WHEN ALLERGIES ATTACK, THE TREATMENTS ARE OUT THERE BUT YOU HAVE TO GO FARTHER THAN THE LOCAL DRUG STORE AISLE TO FIND THEM ALTHOUGH HAY FEVER has long been thought to be little more than a pain in the nose, health experts are now recommending that many allergy sufferers seek a physician’s care and they’re encouraging family physicians to be more vigilant about diagnosing the condition. Allergic disease has suffered for decades from what many medical officials are calling a lack of respect, with patients and physicians themselves failing to take the ailment seriously. “The ….. (Walnut Creek, CA) – March 28, 2000 WHEN ALLERGIES ATTACK, THE TREATMENTS ARE OUT THERE BUT YOU HAVE TO GO FARTHER THAN THE LOCAL DRUG STORE AISLE TO FIND THEM ALTHOUGH HAY FEVER has long been thought to be little more than a pain in the nose, health experts are now recommending that many allergy sufferers seek a physician’s care and they’re encouraging family physicians to be more vigilant about diagnosing the condition. Allergic disease has suffered for decades from what many medical officials are calling a lack of respect, with patients and physicians themselves failing to take the ailment seriously. “The ….. (CA) – March 14, 2000 NOTHING TO SNEEZE AT MEDICAL EXPERTS URGE NEW EMPHASIS IN TREATING ALLERGY SUFFERING SNEEZY, sleepy, dopey, grumpy? Better think about visiting Doc. Although hay fever has long been thought to be little more than a pain in the nose, health experts are now recommending that many allergy sufferers seek a physician’s care — and they’re encouraging family physicians to be more vigilant about diagnosing the condition. Allergic disease has suffered for decades from what many medical officials are calling a lack of respect, with patients — and ….. – February 9, 2000 Should healthcare wear a warning label? When a recent report singled out medical mistakes as a leading cause of death and injury in this country, the moment for serious soul-searching arrived for the health care industry. Nov. 29, 1999, was Black Monday for American medicine. That’s the day the Institute of Medicine released its study “To Err is Human. “Researchers reported that 44, 000 to 98, 000 deaths in the United States each year are caused by medical mistakes. Perhaps the most ….. – February 1, 2000 Family medicine Get a running start against asthma Q. My 14-year-old daughter is on the school track team. The track season is coming up. Are there any new treatments available for Exercise Induced Asthma? – J. T. , Paterson A. Exercise Induced Asthma is a condition that affects up to 15 percent of the population and is characterized by decreased airflow following several minutes of strenuous exercise. The symptoms can occur during or after completing exercise and can affect all age groups, especially children and young adults because of ….. – December 11, 1999 Yes, Asthma and Athletics Are Compatible Dear Dr. Donohue: I am an overweight asthmatic. I am trying to lose weight so that I can look better. Exercise makes it difficult for me to breathe. I have had asthma since I was 3. I seek help in finding a way to participate in normal teen-ager activities. My doctor is no help at all. — N. Y. Most people with asthma can gain an upper hand on the illness so they can exercise and participate in sports. In the 1988 Olympics games, 52 of the 667 athletes suffered from asthma. They had the ….. The Gazette (Cedar Rapids-Iowa City) – December 11, 1999 Asthma, athletics compatible Dear Dr. Donohue: I am an overweight asthmatic. I am trying to lose weight so that I can look better. Exercise makes it difficult for me to breathe. I have had asthma since I was 3. I seek help in finding a way to participate in normal teen-ager activities. My doctor is no help at all. – N. Y. Answer: Most people with asthma can gain an upper hand on the illness so they can exercise and participate in sports. In the 1988 Olympics games, 52 of the 667 athletes suffered from asthma. They had ….